Multiple sclerosis (MS) is a progressive, immune-mediated disorder. That means the system designed to keep your body healthy mistakenly attacks parts of your body that aren’t harmful. The protective coverings of nerve cells are damaged, which leads to diminished function in the brain and spinal cord.
MS is a disease with unpredictable symptoms that can vary in intensity. While some people experience fatigue and numbness, severe cases of MS can cause paralysis, vision loss, and diminished brain function.
MS is a lifelong disease, but it can be managed and researchers are continually looking for more effective treatments.
Early signs and symptoms of MS
Common early signs of multiple sclerosis (MS) include:
- vision problems
- tingling and numbness
- pains and spasms
- weakness or fatigue
- balance problems or dizziness
- bladder issues
- sexual dysfunction
- cognitive problems
For some people, the earliest signs of MS might include clinically isolated syndrome (CIS), neurologic symptoms that last at least 24 hours and can’t be associated with another cause. It includes what’s called demyelination which is damage to myelin, the protective coating that helps to protect nerve cells in the central nervous system.
Although CIS doesn’t necessarily lead to MS, it could be an early sign. Symptoms of a CIS episode could include:
- Optic neuritis. This is damage to the myelin of your optic nerve which may cause vision issues and eye pain.
- Lhermitte’s sign. This condition is caused by a demyelinating lesion on the spinal cord that causes a tingling or shock feeling going down the back and neck, especially when you bend your neck down.
- Transverse myelitis. Transverse myelitis is when the spinal cord is involved and can cause muscle weakness, numbness, and other issues.
An MRI can sometimes be a useful tool in helping to determine if there’s only been one episode of CIS or multiple episodes, which may indicate MS.
Common MS symptoms
Primary symptoms of MS stem from the damage to the protective nerve covering, the myelin. Your doctors can help you manage these symptoms using medication, occupational therapy, and physical therapy.