— Two trials have reported data, and more are underway…
Should multiple sclerosis (MS) patients stop disease-modifying treatment (DMT) as they get older?
The answer depends on several factors, noted John Corboy, MD, of the Rocky Mountain MS Center at the University of Colorado in Aurora, at the 2025 Americas Committee for Treatment and Research in Multiple Sclerosis (ACTRIMS) Forum.
“Many patients are discontinuing DMTs as they age, and there is little data to guide them as to risks or benefits,” Corboy told MedPage Today.
Observational studies and two randomized controlled trials consistently suggest that, in general, disease recurrence after DMT discontinuation diminishes with age and patients may wish to consider stopping MS drugs.