The human brain is made up of two types of tissue: gray matter, which is composed of nerve cells, and white matter, which is composed of bundles of nerve fibers that connect nerve cells in different areas of the brain and carry nerve impulses between them.

“The traditional way of thinking is that MS is primarily a white matter disease,” says Lael Stone, MD, formerly a neurologist specializing in multiple sclerosis (MS) at the Cleveland Clinic in Ohio.

But “most [experts] in MS at this point would say that there is clearly involvement of both white and gray matter,” says Dr. Stone. Still, “you could put 10 MS specialists in a room, and they would have a hard time agreeing on which is more important and which comes first.” The read this article is its entirety click this link: https://www.everydayhealth.com/multiple-sclerosis/treatment/ms-brain-white-matter-gray-matter-mri-research/